Can You Prevent Dementia? These 10 Strategies May Help – 3X4 Genetics Skip to content

Can You Prevent Dementia? These 10 Strategies May Help


Dementia affects millions of people worldwide, with more than 
10 million new cases diagnosed each year.

But can you prevent dementia?

Science suggests that lifestyle choices can play a major role in protecting brain health.

A healthy diet, exercise, sleep, and mental stimulation can help protect brain health and may reduce the risk of cognitive decline.

Many believe dementia is an inevitable part of aging, but that’s a myth.

Brain changes can begin decades before symptoms appear, meaning what you do today can shape your cognitive health for years to come.

This article explores whether dementia can be prevented and breaks down 10 science-backed strategies to strengthen memory, protect neural pathways, and promote lifelong brain function. 

Your genes set the foundation, but your daily habits shape the outcome. Taking the right steps today can support cognitive health for years to come.

Is Dementia an Inevitable Part of Aging?

Dementia refers to conditions that cause cognitive decline, affecting memory, reasoning, and daily life.

While aging raises the risk, research confirms it isn’t unavoidable.

Brain changes can begin decades before symptoms appear, making early action essential for long-term cognitive health.

So, how can you tell if memory lapses are normal or a sign of something more concerning?

Forgetting a name or misplacing keys happens to everyone. Slower recall and minor lapses occur with age but don’t interfere with daily life.

Dementia, on the other hand, involves persistent memory loss, difficulty handling familiar tasks, and confusion about time or place. Mood and personality shifts may also develop.

Recognizing these differences is the first step. Now, let’s explore the different types of dementia and their effects on brain function.

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The Different Types of Dementia and Why They Matter 

Hands cradling a brain cutout, highlighting the question: Can you prevent dementia?

Each type of dementia has distinct causes, symptoms, and progression patterns. But can you prevent dementia from developing or slow it down once it starts?

Early detection plays a key role in managing symptoms and improving quality of life.

1. Alzheimer’s Disease 

The most common form of dementia, Alzheimer’s, accounts for 60-70% of all cases. It is driven by the buildup of amyloid plaques and tau tangles, which damage brain cells and disrupt memory, thinking, and problem-solving.

Symptoms include:

  • Memory loss that interferes with daily life.
  • Difficulty solving problems or making decisions.
  • Confusion about time, place, or familiar people.

2. Vascular Dementia 

Vascular dementia affects about 20% of people with dementia and is caused by reduced blood flow to the brain, often due to strokes or mini-strokes.

This can result in:

  • Slower thinking and problem-solving.
  • Memory issues that vary in severity.
  • Trouble with focus, organization, and decision-making.

3. Lewy Body Dementia 

Lewy Body Dementia (LBD) accounts for 10-15% of dementia cases and is caused by protein deposits (Lewy bodies) in brain cells. It shares symptoms with both Alzheimer’s and Parkinson’s, including:

  • Vivid hallucinations and disrupted sleep.
  • Fluctuating cognitive abilities; some days seem normal, while others show major confusion.
  • Tremors, muscle stiffness, and movement difficulties.

4. Frontotemporal Dementia (FTD) 

Frontotemporal Dementia accounts for about 2-5% of dementia cases and typically affects individuals between 45 and 65 years old. Unlike Alzheimer’s, FTD doesn’t start with memory loss. Instead, it impacts personality, behavior, and language.

Symptoms include:

  • Impulsive, inappropriate, or erratic behavior.
  • Emotional detachment and lack of empathy.
  • Speech and language difficulties.

5. Mixed Dementia 

Many individuals develop more than one type of dementia, most commonly Alzheimer’s and vascular dementia. This combination can:

  • Speed up cognitive decline.
  • Cause a mix of memory loss and problem-solving difficulties.
  • Require a multi-layered care approach.

6. Other Types of Dementia 

Early detection and understanding different types of dementia are crucial, but the next step is even more important, and that is taking action.

While there’s no guaranteed way to prevent dementia, research-backed strategies can help protect brain health and reduce risk.

Can You Prevent Dementia? 10 Science-Backed Ways to Lower Your Risk

Dementia doesn’t happen overnight. But can you prevent dementia before symptoms even begin?

Brain changes can begin as early as your 40s or 50s, offering a crucial opportunity to take action. Making changes during this window of prevention may help slow or even prevent cognitive decline.

Preventing dementia in old age starts with recognizing risk factors early.

Biological changes associated with dementia, such as plaque buildup, vascular damage, and neuroinflammation, begin long before memory loss becomes noticeable.

But proactive lifestyle choices can support brain health before symptoms take hold.

Some dementia risk factors are unavoidable, like age and genetics, while others, such as diet, exercise, and sleep, are within your control.

Research shows that taking action in midlife can significantly lower dementia risk.

So what are the most effective steps? Let’s explore 10 proven strategies to keep your brain sharp for years to come.

1. Food Fight: The Best Foods for Brainpower 

A brain-healthy diet can lower dementia risk by up to 30%. Two of the best:

  • Mediterranean Diet: Packed with fruits, vegetables, whole grains, olive oil, and fish, it fights inflammation and supports cognitive function.

  • MIND Diet: A blend of Mediterranean and DASH diets, prioritizing leafy greens, berries, nuts, and whole grains while limiting processed foods and sugar. It’s linked to a slower cognitive decline.

Brain-Boosting Nutrients 

  • Omega-3s & Polyphenols: Found in fatty fish, nuts, and colorful fruits, they reduce neuroinflammation, a key driver of cognitive decline.
  • Antioxidants: Found in berries, dark chocolate, and green tea, they combat oxidative stress, protecting brain cells.

Actionable Tip: Add leafy greens, nuts, and olive oil to your meals daily. Eat fatty fish like salmon twice a week to support brain health. Avoid processed foods as much as possible.

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2. Step Up Your Brain Health 

Can dementia be slowed with exercise? Absolutely!

Your brain thrives on movement, and exercise protects neurons, strengthens memory, and lowers dementia risk.

How Exercise Fuels Brain Health 

  • Boosts BDNF (Brain-Derived Neurotrophic Factor): This protein helps neurons grow, survive, and connect, enhancing memory and learning.

  • Improves Blood Flow: More oxygen and nutrients reach the brain, reducing inflammation and supporting cognitive function.

  • Lowers Stress & Enhances Sleep: Exercise regulates stress hormones and improves deep sleep, both critical for brain health.

How Much Movement Do You Need? 

  • Cardio: 150+ minutes per week of brisk walking, cycling, or swimming supports brain resilience.

  • Strength Training: At least twice a week of weight training or resistance exercises preserves brain function and muscle health.

Actionable Tip: Take a 10-minute brisk walk today. Even small steps help protect brain function over time. Even short bursts of movement enhance neuroplasticity, lower dementia risk, and sharpen mental agility.

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3. Sleep: The Brain’s Reset Button 

Woman sleeping peacefully, as quality sleep is one way to slow down dementia risk


Your brain detoxes while you sleep, clearing waste, strengthening memory, and protecting against cognitive decline.

Poor sleep disrupts these processes, increasing dementia risk.

Why Deep Sleep Matters for Brain Health 

  • Flushes Brain Toxins: Deep sleep assists in removing beta-amyloid, a protein linked to Alzheimer’s.

  • Strengthens Memory & Learning: Sleep reinforces neural connections and supports cognition.

  • Poor Sleep = Higher Dementia Risk: Disrupted sleep accelerates beta-amyloid buildup, increasing Alzheimer’s risk.

How to Improve Sleep & Protect Your Brain 

  • Address Sleep Disorders: Conditions like sleep apnea limit oxygen flow and disrupt deep sleep. Treatments like CPAP therapy restore healthy sleep cycles.
  • Stick to a Sleep Schedule: Go to bed and wake up at the same time daily to regulate your body clock.
  • Reduce Screen Time Before Bed: Blue light blocks melatonin, making it harder to fall asleep.
  • Optimize Your Sleep Space: Keep your room cool, dark, and quiet; use blackout curtains and white noise if needed.
  • Wind Down Before Bed: Try meditation, deep breathing, or gentle stretching to calm the mind.

Actionable Tip: Set a consistent bedtime and limit screens before bed; small changes can lead to big brain benefits. 

MYTH or FACT? "Waking up often at night is just a normal part of aging."

MYTH!

Poor sleep impacts brain health. Frequent night awakenings increase beta-amyloid buildup, a key protein linked to Alzheimer’s disease and dementia.

How Night time Awakenings Harm Brain Health

  • Disrupts deep sleep
  • Accelerates beta-amyloid buildup
  • Weakens cognitive function

Quality sleep is a pillar of dementia prevention. Fixing sleep disruptions reduces Alzheimer’s risk, sharpens memory, and strengthens long-term cognitive function.

4. The Stress-Dementia Link—And How to Break It 

Stress physically changes your brain.

Chronic stress shrinks the hippocampus, weakens memory, and increases dementia risk. But the right strategies can protect your brain.

How Stress Harms Brain Health 

  • Shrinks the Hippocampus: Stress damages neurons, making memory recall harder.
  • Spikes Cortisol: High cortisol levels accelerate brain aging and cognitive decline.
  • Raises Dementia Risk: Chronic stress speeds up cognitive deterioration over time.

How to Reduce Stress & Protect Your Brain 

  • Try Mindfulness & Meditation: Just 5 minutes of deep breathing can lower cortisol.
  • Stay Socially Connected: Engaging with others reduces stress and sharpens cognition.
  • Adopt Therapy & Coping Strategies: Techniques like CBT help manage stress before it affects your brain.

Actionable Tip: Pause. Take 5 deep breaths right now. Small habits lead to lasting brain benefits. 

5. Heart Health = Brain Health 

Your heart fuels your brain. Poor circulation reduces oxygen flow to the brain, increasing the risk of dementia. Hence, protecting your heart protects your memory.

How Heart Health Impacts Brain Function 

  • High Blood Pressure: Hypertension in midlife raises dementia risk. Managing it keeps your brain sharp.
  • Diabetes: High blood sugar damages blood vessels, starving brain cells of oxygen.
  • High Cholesterol: LDL (bad) cholesterol clogs arteries, restricting blood flow and increasing dementia risk.

A large proportion of dementia cases could be prevented by improving circulation. More oxygen to the brain = stronger cognition, better focus, and long-term brain protection.

Actionable Tip: Get your blood pressure checked today. Small steps now = better brain health later.

6. The Best Brain Exercises - No Gym Required! 


Your brain craves challenge. The more you learn, problem-solve, and explore, the stronger your cognitive reserve.

Consistently engaging in activities that challenge your mind is one of the most effective things you can do to prevent dementia.

How Mental Stimulation Protects Brain Health

Cognitive health is all about variety. The best approach combines mental stimulation, physical activity, social engagement, and nutrition for long-term brain protection.

Actionable Tip: Spend 10 minutes today learning something new: a word, skill, or trivia fact. Small daily challenges build a more resilient brain.

MYTH or FACT? "Doing crossword puzzles daily will prevent dementia."

❌ MYTH!

While puzzles keep your brain active, they aren’t enough to prevent dementia. True cognitive protection comes from variety, challenging different brain functions through diverse activities.

Why Crosswords Alone Don't Cut It

  • Boosts Specific Skills: Crosswords improve vocabulary and recall but don't strengthen all cognitive areas.
  • Limited Impact: While they help maintain mental sharpness, they don't significantly lower dementia risk unless combined with other activities.

What Actually Strengthens Brain Health?

  • Mix up mental workouts. Read, learn a language, play chess, or try music training.
  • Move your body. Exercise fuels brain plasticity.
  • Community engagement reduces stress and keeps your brain engaged.
  • The Mediterranean diet supports cognitive longevity.
  • Keep learning and challenging your brain with new skills.
  • Practice delayed gratification. This helps boost dopamine production which is important to support memory pathways.

Dementia prevention requires balance. A holistic lifestyle combining cognitive, physical, and social engagement is the most effective way to keep your brain strong.


7. Early Detection and How It Helps 

The earlier you detect Alzheimer’s, the better your chances of slowing it down. But can you prevent dementia entirely with early detection?

While no cure exists, identifying risks sooner allows for better interventions. 

Breakthroughs in Early Detection 

  • Blood-Based Biomarkers: Tests like PrecivityAD2 detect Alzheimer’s with 90% accuracy, measuring key proteins like p-tau217 and amyloid-beta—years before noticeable decline.

  • Tau Protein Research: New markers (p-tau217, p-tau262, p-tau356) predict Alzheimer’s before traditional brain scans can detect it.

  • Voice-Based Detection: AI-powered tools analyze speech patterns for subtle signs of cognitive decline, offering a non-invasive, accessible screening method.

  • Cell-Free DNA Testing: Scientists are studying blood-based DNA markers that signal early neurodegeneration.

If you’re over 40, especially with a family history of dementia, early cognitive health screenings could be life-changing.

Actionable Tip: Ask your doctor about new blood-based screening options to detect Alzheimer’s before symptoms appear. With advancements in biomarker testing, AI diagnostics, and non-invasive screening, Alzheimer’s can now be spotted earlier and managed proactively.

8. Protect Your Hearing, Protect Your Brain 

Hearing loss is a major risk factor for dementia. Addressing hearing loss can slow cognitive decline by nearly 50%.

How Hearing Loss Impacts Brain Health

  • Dementia Risk Increases with Hearing Decline: Every 10 dB drop in hearing ability significantly raises the risk of cognitive decline.

  • Hearing Aids Can Help: The ACHIEVE trial found that older adults with hearing aids reduced cognitive decline by 48% over three years.

Actionable Tip: Schedule a hearing test if you haven’t had one in the last year. Practice active listening by engaging in conversations and challenging auditory tasks.

9. Stay Social, Because Your Brain Depends on It 

Group of friends being social, sharing a healthy meal to prevent dementia

Hearing loss often leads to withdrawal from social interactions, which is one of the biggest predictors of dementia.

Social engagement keeps the brain sharp. Conversations, group activities, and staying connected stimulate cognition and reduce dementia risk.

Actionable Tip: Call or visit a friend or family member today, even a short conversation helps! You can also join a class, club, or volunteer group to stay socially engaged. 

10. Avoid Head Injuries - Protect Your Brain for Life 

Head injuries increase dementia risk, especially repeated concussions linked to chronic traumatic encephalopathy (CTE).

Wearing seatbelts, using helmets, and reducing fall risks protect long-term brain health.

Actionable Tip: Make your home fall-proof. Install grab bars in bathrooms, improve lighting, and remove tripping hazards.

Is Dementia Written in Your Genes?

Two women enjoying a walk outdoors, a simple way to prevent dementia

Many people ask: is dementia genetic? Can you still prevent it if it is?

Your genes may influence your chances, but they don’t define your future. While some genetic variants increase susceptibility, your choices still matter.

Knowing how to prevent dementia and Alzheimer's through targeted lifestyle choices significantly reduces your risk.

Key Genes Linked to Dementia Risk 

1. APOE ε4 

A strong genetic risk factor for Alzheimer’s. One copy raises the risk, and two copies increase it further, but it’s not a guarantee of developing dementia.

2. APP, PSEN1, PSEN2 

Variations in these genes (APP, PSEN1, and PSEN2) are linked to early-onset Alzheimer’s (before 65), often running in families. Though rare, these variations are considered high penetrance, meaning they can directly cause the condition in individuals who carry them. Genetic testing for these variations is available, but due to their significant implications, it should only be pursued after consultation with a genetic counselor.

Can You Prevent Dementia If You Have a Genetic Risk? 

A genetic predisposition is not a diagnosis, so can you prevent dementia even if you have high-risk genes?

Research shows that up to 45% of dementia cases may be preventable with the right lifestyle interventions.

Who Might Benefit from Genetic Testing? 

  • Those with a family history of dementia, especially early-onset cases.
  • Individuals seeking personalized prevention strategies.
  • Anyone wanting to understand their unique genetic blueprint for brain health.

Genes + Choices = Brain Health

Genetic testing is a tool, not a fate. Your genes provide insight, but your choices shape the outcome.

MYTH or FACT? "Dementia only affects people over 65."

MYTH

Dementia can start as early as your 40s. Early-onset dementia (EOD) accounts for up to 9% of all cases , disrupting careers, family life, and daily independence.

While genetics can play a role, lifestyle and health factors are major contributors:

  • Smoking, alcohol use, poor diet: Increases inflammation and speeds up cognitive decline.
  • Diabetes, high blood pressure, heart disease: Impacts brain circulation and function.
  • Mental health matters: Chronic stress, depression, and social isolation increase risk.

Dementia is more than an aging issue-it's a brain health issue. But what can you do to prevent dementia?

Research points to practical, everyday changes that help protect your brain. Recognizing early warning signs can lead to timely interventions that slow progression and improve quality of life.

Dementia doesn't wait for retirement, nor should you.

Small Changes, Big Impact. Your Brain’s Action Plan

Dementia is largely shaped by the choices you make every day.

But can dementia be reversed if caught early through lifestyle adjustments? While a complete reversal isn’t possible, they can significantly decline the risk, even if you have a genetic predisposition.

You must:

  • Move more. Even small amounts of exercise can protect brain function.
  • Eat smarter. A Mediterranean-style diet fuels cognitive health.
  • Prioritize sleep & stress management. Better rest = better brainpower.
  • Stay socially & mentally engaged. Learning and connection build cognitive resilience.

Every small change adds up. A short walk, a healthy meal, a deep conversation- all of it strengthens your brain for the future.

The best time to start is now.

Want a more personalized approach? 3X4 Genetics helps uncover your unique genetic blueprint to help you make data-driven decisions for lifelong brain health.

Your genes + your choices = your brain’s future. 

Let’s make it a strong one.

FAQs

At what age does dementia start?

Most cases develop after age 65, but dementia can start earlier. Early-onset dementia, affecting people in their 40s or 50s, is less common but still significant.

What is the number one cause of dementia?

Alzheimer’s disease is the leading cause, responsible for 60-70% of dementia cases. It gradually damages brain cells, affecting memory, thinking, and behavior.

Can dementia be prevented if caught early?

While there’s no cure, early detection can slow its progression. Lifestyle changes, such as exercise, brain-healthy nutrition, and cognitive training, can help reverse symptoms, reduce risk and improve quality of life.

Is dementia 100% preventable?

No, but risk can be reduced. Genetics and age play a role, but modifiable factors like diet, exercise, avoiding toxin exposures, treating infections and heart health can significantly lower the chances of developing dementia.

Annelie Smith RD IFNCP

Head of Clinical and Mentorship

Annelie is a nutrigenomics expert with 15+ years of experience applying genetic insights in clinical practice. A certified clinician, she has worked across critical care, executive wellness, and elite sports nutrition. As a founding member of 3X4 Genetics, Annelie now leads Clinical and Mentorship, guiding both her team and business partners.